DFG Collaborative Research Centres

Collaborative Research Centres (CRC), funded by the German Research Foundation (DFG), are institutions established at the university for a period of up to 12 years that enable researchers to pursue innovative research projects, crossing the boundaries of traditional subjects and disciplines. In a variation of the programme, the „CRC/Transregio“, up to three universities cooperate in pursuit of a joint research aim.

Heidelberg University as Applicant Institution

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CRC/TRR 156 The Skin as Sensor and Effector Organ Orchestrating Local and Systemic Immune Responses ^{since 2015}	Prof. Dr. Alexander Enk	Medical Faculty Heidelberg
CRC/TRR 179 Determinants and dynamics of elimination versus persistence of hepatitis virus infection ^{since 2016}	Prof. Dr. Ralf Bartenschlager	Medical Faculty Heidelberg
CRC/TRR 265 Loss and regaining control in addictions ^{since 2019}	Prof. Dr. Rainer Spanagel	Medical Faculty Mannheim
CRC 1129 Integrative Analysis of Pathogen Replication and Spread ^{since 2014}	Prof. Dr. Hans-Georg Kräusslich	Medical Faculty Heidelberg
CRC 1158 From Nociception to Chronic Pain: Structure-function Properties of Neural Pathways and Their Reorganisation ^{since 2015}	Prof. Dr. Rohini Kuner	Medical Faculty Heidelberg
CRC 1225 Isolated Quantum Systems and Universality under Extreme Conditions (ISOQUANT) ^{since 2016}	Prof. Dr. Jürgen Berges	Institute for Theoretical Physics
CRC 1249 N-Heteropolycycles as Functional Materials ^{since 2017}	Prof. Dr. Petra Tegeder	Institute for Physical Chemistry
CRC 1324 Mechanisms and functions of WnT signaling ^{since 2017}	Prof. Dr. Michael Boutros	Medical Faculty Heidelberg
CRC 1366 Vascular Control of Organ Function ^{since 2019}	Prof. Dr. Hellmut Augustin	Medical Faculty Mannheim
CRC 1389 Understanding and Targeting Resistance in Glioblastoma ^{since 2019}	Prof. Dr. Wolfgang Wick	Medical Faculty Heidelberg
CRC 1550 Molecular Circuits of Heart Disease ^{since 2020}	Prof. Dr. Johannes Backs	Medical Faculty Heidelberg
CRC 1638 Cellular membrane remodelling – how changing form creates function ^{since 2024}	Prof. Dr. Michael Meinecke	Heidelberg University Biochemistry Center (BZH)
CRC 1671 Heimat(en): Phänomene, Praktiken, Darstellungen ^{since 2024}	Prof. Dr. Christiane Wiesenfeldt	Department of Musicology
CRC 1709 Cellular Plasticity in Myeloid Malignancies: From Mechanisms to Therapies ^{starting in October 2025}	Prof. Dr. Carsten Müller-Tidow	Medical Faculty Heidelberg

Heidelberg University as Co-Applicant Institution

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CRC/TRR 186 Molecular Switches: Spatio-temporal Control of Cellular Signal Transmission ^{since 2016}	Freie Universität Berlin	Prof. Dr. Walter Nickel Heidelberg University Biochemistry Center	Heidelberg University Biochemistry Center (BZH) Medical Faculty Mannheim Medical Faculty Heidelberg Centre for Molecular Biology (ZMBH)
CRC/TRR 191 Symplectic Structures in Geometry, Algebra and Dynamics ^{since 2017}	University of Cologne	Prof. Dr. Peter Albers Institute for Mathematics	Institute for Mathematics Interdisciplinary Center for Scientific Computing (IWR)
CRC/TRR 319 RMaP: RNA Modification and Processing ^{since 2021}	Johannes Gutenberg University Mainz	Prof. Dr. Andres Jäschke Institute of Pharmacy and Molecular Biotechnology (IPMB)	Institute of Pharmacy and Molecular Biotechnology (IPMB) Medical Faculty Mannheim Medical Faculty Heidelberg Heidelberg University Biochemistry Center (BZH)
CRC/TRR 326 Geometry and Arithmetic of Uniformized Structures ^{since 2021}	Goethe University Frankfurt	Prof. Dr. Alexander Schmidt Institute for Mathematics	Institute for Mathematics Interdisciplinary Center for Scientific Computing (IWR)
CRC/TRR 379 Neuropsychobiology of Aggression: A Transdiagnostic Approach in Mental Disorders ^{since 2024}	Rheinisch-Westfälische Technische Hochschule Aachen University	Prof. Dr. Sabine Herpertz Medical Faculty Heidelberg	Medical Faculty Heidelberg Medical Faculty Mannheim Central Institute of Mental Health (ZI)

CRC and CRC/Transregios with Participation

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CRC 1242 Non-Equilibrium Dynamics of Condensed Matter in the Time Domain ^{since 2016}	University of Duisburg-Essen (UDE)	Kirchhoff-Institute for Physics
CRC/TRR 152 TRiPs to Homeostasis: Maintenance of Body Homeostasis by Transient Receptor Potential Channel Modules ^{since 2014}	Ludwig-Maximilians-Universität München (LMU)	Medical Faculty Heidelberg
CRR/TRR 185 Open System Control of Atomic and Photonic Matter (OSCAR) ^{since 2016}	University of Kaiserslautern-Landau	Kirchhoff-Institute for Physics
CRC/TRR 237 Nucleic Acid Immunity ^{since 2018}	Ludwig Maximilian University of Munich (LMU)	Medical Faculty Heidelberg
CRC/TRR 257 P3H: Particle Physics Phenomenology after the Higgs Discovery ^{since 2019}	Karlsruhe Institute of Technology (KIT)	Institute for Theoretical Physics
CRC/TRR 384 Inhibitory neurons: shaping the cortical code (IN-CODE) ^{since 2024}	University of Freiburg	Medical Faculty Heidelberg
CRC/TRR 392 Molecular evolution in prebiotic environments ^{since 2024}	Ludwig Maximilian University of Munich (LMU)	Institute of Pharmacy and Molecular Biotechnology (IPMB)
CRC/TRR 412 Metabolic dysfunction-associated steatotic liver disease: Translating mechanisms to tailored therapeutic concepts ^{starting in October 2025}	Freie Universität Berlin and Humboldt-Universität zu Berlin	Medical Faculty Heidelberg
CRC 1101 pH in the TGN/EE as specificity determinant in the post-Golgi trafficking (A02) ^{since 2014}	University of Tübingen	Centre for Organismal Studies (COS) BioQuant
CRC 1177 Molecular and Functional Characterization of Selective Autophagy ^{since 2016}	Goethe University Frankfurt	Medical Faculty Mannheim
CRC 1211 Earth - Evolution at the Dry Limit ^{since 2016}	University of Cologne	Institute of Geography Centre for Organismal Studies (COS)
CRC 1261 Magnetoelectric Sensors: From Composite Materials to Biomagnetic Diagnostics ^{since 2016}	Kiel University	Medical Faculty Heidelberg Institute for Molecular Systems Engineering and Advanced Materials (IMSEAM)
CRC 1328 Adenine Nucleotides in Immunity and Inflammation ^{since 2018}	University of Hamburg	Medical Faculty Heidelberg
CRC 1381 Dynamic organization of cellular protein machineries: From biogenesis and modular assembly to function ^{since 2019}	University of Freiburg	Centre for Molecular Biology (ZMBH)
CRC 1436 Neural resources of cognition ^{since 2021}	Otto von Guericke University of Magdeburg	Institute of Inorganic Chemistry (ACI)
CRC 1459 Intelligent matter: From responsive to adaptive nanosystems ^{since 2021}	University of Münster	Kirchhoff-Institute for Physics
CRC 1487 Iron, upgraded! ^{since 2022}	Technical University of Darmstadt	Institute of Inorganic Chemistry (ACI)
CRC 1528 Cognition of Interaction ^{since 2022}	University of Göttingen	Medical Faculty Heidelberg
CRC 1531 Damage Control by the Stroma-Vascular Compartment ^{since 2022}	Goethe University Frankfurt	Medical Faculty Heidelberg Medical Faculty Mannheim

last updated on 2025/12/16

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DFG Collaborative Research Centres

Heidelberg University as Applicant Institution

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Heidelberg University as Co-Applicant Institution

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CRC and CRC/Transregios with Participation

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