Wissenschaftliche Gesamtkoordination

Dr. Irina Idler

Contact

Nationales Centrum für Tumorerkrankungen (NCT) Heidelberg
Im Neuenheimer Feld 460
69120 Heidelberg

Tel.: +49 (0)6221- 56 38 695
E-Mail: irina.idler@nct-heidelberg.de

Curriculum Vitae

05/2018-now	Scientific Coordinator of the EURAT Project Group, NCT, Heidelberg, Head of Project group: Prof. Dr. Dr. E. Winkler
02/2018 - 04/2018	Clinical Affairs Manager, Underwriters Laboratories-Emergo, CRO-Emergo, Ochsenhausen Medical Director: Dr. J. Laufer
02/ 2017- 02/2018	Project Manager Clinical Studies, Underwriters Laboratories, Medical Device Testing (UL MDT), Ochsenhausen Head of CRO: Dr. D. Falke
06/2011- 01/2017	Postdoctoral Scientist, German Cancer Research Center (DKFZ), University Hospital Ulm, Department Internal Medicine III, Cooperation Unit „Mechanisms of Leukemogenesis” headed by PD. Dr. D. Mertens, close collaboration with Prof. Dr. S. Stilgenbauer
12/2009- 09/2010	Teacher, Kilian- von Steiner School for Vhemical and Ecologic, Technical Assistant
10/2007 - 08/2009	Postdoctoral scientist, University Hospital in Ulm, Internal Medicine III,German Cancer Research Center (DKFZ), Cooperation Unit „Mechanisms of Leukemogenesis”, headed by PD. Dr. D. Mertens
10/2006- 03/2007	Associate researcher, Systems Biology Network „SB Cancer“, German Cancer Center (DKFZ) in Heidelberg, coordinated by Prof. Karsten Rippe and Dr. Daniel Mertens
12/2004- 10/2006	Maternity leave

Education

09/2015-now	Master in „Clinical Trial Management“ Beuth Hochschule für Technik in Berlin („Fernstudieninstitut Beuth“)
09/2009 – 06/2010	Education for „Teacher formation in Vocational Schools“ Staatliches Seminar für Didaktik und Lehrerbildung Weingarten (Berufliche Schulen und Gymnasien), Baden Württemberg
12/1999 – 11/2004	PhD Thesis Ruprecht-Karls-Universität Heidelberg, Center for Molecular Biology Heidelberg (ZMBH): “Analysis of the cellular and humoral immune response against the Merozoite-Surface-Protein-1 of the malaria parasite Plasmodium falciparum”, Supervisor: Prof. H. Bujard
01/1999 – 09/1999	Diploma German Cancer Center Heidelberg (DKFZ): “Mutation Analysis of the ATM gene in Mantle Cell Lymphoma“, Department of „Molecular Genetics“, Supervisor: Prof. P. Lichter
06/1996 – 08/1999	Diploma studies in Biology at the Ruprecht-Karls-Universität, Heidelberg, Molecular Biology, Pharmacology und Zoology
10/1993 – 04/1996	Study of Biology at the University Stuttgart-Hohenheim, Bachelor in Physics, Chemistry, Botany und Zoology
1985–1993	Georg Büchner Gymnasium Winnenden, Chisipite High School, Harare, Zimbabwe

Publications (Auswahl)

Opel, D., A. Schnaiter, D. Dodier, M. Jovanovic, A. Gerhardinger, I. Idler, D. Mertens, L. Bullinger, S. Stilgenbauer and S. Fulda (2015). "Targeting inhibitor of apoptosis proteins by Smac mimetic elicits cell death in poor prognostic subgroups of chronic lymphocytic leukemia." Int J Cancer 137(12): 2959-2970. IF 5.007
Garding, A., N. Bhattacharya, R. Claus, M. Ruppel, C. Tschuch, K. Filarsky, I. Idler, M. Zucknick, M. Caudron-Herger, C. Oakes, V. Fleig, I. Keklikoglou, D. Allegra, L. Serra, S. Thakurela, V. Tiwari, D. Weichenhan, A. Benner, B. Radlwimmer, H. Zentgraf, S. Wiemann, K. Rippe, C. Plass, H. Dohner, P. Lichter, S. Stilgenbauer and D. Mertens (2013). "Epigenetic upregulation of lncRNAs at 13q14.3 in leukemia is linked to the In Cis downregulation of a gene cluster that targets NF-kB." PLoS Genet 9(4): e1003373. IF 8.694.
Garding, A., N. Bhattacharya, S. Haebe, F. Muller, D. Weichenhan, I. Idler, K. Ickstadt, S. Stilgenbauer and D. Mertens (2013). "TCL1A and ATM are co-expressed in chronic lymphocytic leukemia cells without deletion of 11q." Haematologica 98(2): 269-273. IF 5.
Bhattacharya, N., S. Diener, I. S. Idler, T. F. Barth, J. Rauen, A. Habermann, T. Zenz, P. Moller, H. Dohner, S. Stilgenbauer and D. Mertens (2011). "Non-malignant B cells and chronic lymphocytic leukemia cells induce a pro-survival phenotype in CD14+ cells from peripheral blood." Leukemia 25(4): 722-726. IF 9.561
Bhattacharya, N., S. Diener, I. S. Idler, J. Rauen, S. Habe, H. Busch, A. Habermann, T. Zenz, H. Dohner, S. Stilgenbauer and D. Mertens (2011). "Nurse-like cells show deregulated expression of genes involved in immunocompetence." Br J Haematol 154(3): 349-356. IF 4.942
Idler, I., N. Bhattacharya, H. Dohner, S. Stilgenbauer and D. Mertens (2011). "Immune modulatory agents in hematopoietic malignancies." Cancer Treat Rev 37 Suppl 1: S2-7. IF 6.811
Bhattacharya, N., A. Sarno, I. S. Idler, M. Fuhrer, T. Zenz, H. Dohner, S. Stilgenbauer and D. Mertens (2010). "High-throughput detection of nuclear factor-kappaB activity using a sensitive oligo-based chemiluminescent enzyme-linked immunosorbent assay." Int J Cancer 127(2): 404-411. IF 4.942
Giannopoulos, K., D. Mertens, A. Buhler, T. F. Barth, I. Idler, P. Moller, A. Krober, J. Greiner, S. Chocholska, A. Dmoszynska, J. Rolinski, H. Dohner, S. Stilgenbauer and M. Schmitt (2009). "The candidate immunotherapeutical target, the receptor for hyaluronic acid-mediated motility, is associated with proliferation and shows prognostic value in B-cell chronic lymphocytic leukemia." Leukemia 23(3): 519-527. IF 8.634
Idler, I., K. Giannopoulos, T. Zenz, N. Bhattacharya, M. Nothing, H. Dohner, S. Stilgenbauer and D. Mertens (2009). "Lenalidomide treatment of chronic lymphocytic leukaemia patients reduces regulatory T cells and induces Th17 T helper cells." Br J Haematol 148(6): 948-950. IF 4.942
Mertens, D., A. Philippen, M. Ruppel, D. Allegra, N. Bhattacharya, C. Tschuch, S. Wolf, I. Idler, T. Zenz and S. Stilgenbauer (2009). "Chronic lymphocytic leukemia and 13q14: miRs and more." Leuk Lymphoma 50(3): 502-505. IF 2.492
Schaffner, C., I. Idler, S. Stilgenbauer, H. Dohner and P. Lichter (2000). "Mantle cell lymphoma is characterized by inactivation of the ATM gene." Proc Natl Acad Sci U S A 97(6): 2773-2778. IF 9.643

Anmerkung: Die Gesamtkoordination der EURAT-Gruppe hatte bis August 2013 Frau Dr. Grit Schwarzkopf, von 2013-2014 Herr Dr. Christoph Schickhardt und von 2014-28.02.2017 Herr Sebastian Schuol inne. Die Stelle wurde von 02.2017- 05.2018 durch Herrn Dr. Christoph Schickhardt kommissarisch vertreten.

Responsible: Email

Latest Revision: 2019-12-09