Wissenschaftliche Gesamtkoordination

 

Dr. Irina Idler    

                                                                                                            

Kontakt                                                                              

Nationales Centrum für Tumorerkrankungen (NCT) Heidelberg                                
Im Neuenheimer Feld 460
69120 Heidelberg

Tel.: +49 (0)6221- 56 38 695
E-Mail: irina.idler@nct-heidelberg.de

 

 


Curriculum Vitae

 

05/2018-now

Scientific Coordinator of the EURAT Project Group,
NCT, Heidelberg,
Head of Project group: Prof. Dr. Dr. E. Winkler

02/2018 - 04/2018

Clinical Affairs Manager,
Underwriters Laboratories-Emergo,
CRO-Emergo, Ochsenhausen
Medical Director: Dr. J. Laufer

02/ 2017- 02/2018

Project Manager Clinical Studies,
Underwriters Laboratories, Medical Device Testing (UL MDT), Ochsenhausen

Head of CRO: Dr. D. Falke

06/2011-
01/2017

Postdoctoral Scientist,
German Cancer Research Center (DKFZ), University Hospital Ulm, Department Internal Medicine III, Cooperation Unit „Mechanisms of Leukemogenesis” headed by PD. Dr. D. Mertens, close collaboration with Prof. Dr. S. Stilgenbauer

12/2009- 09/2010

Teacher,
Kilian- von Steiner School for Vhemical and Ecologic, Technical Assistant

10/2007 -
08/2009

Postdoctoral scientist,
University Hospital in Ulm, Internal Medicine III,German Cancer Research Center (DKFZ), Cooperation Unit „Mechanisms of Leukemogenesis”, headed by PD. Dr. D. Mertens

10/2006-
03/2007

Associate researcher,
Systems Biology Network „SB Cancer“, German Cancer Center (DKFZ) in Heidelberg, coordinated by Prof. Karsten Rippe and Dr. Daniel Mertens

 

12/2004-
10/2006

Maternity leave

  

Education

 

09/2015-now

Master in Clinical Trial Management
Beuth Hochschule für Technik in Berlin („Fernstudieninstitut Beuth“)

09/2009 – 06/2010

Education for „Teacher formation in Vocational Schools“
Staatliches Seminar für Didaktik und Lehrerbildung Weingarten (Berufliche Schulen und Gymnasien), Baden Württemberg

12/1999 – 11/2004

PhD Thesis Ruprecht-Karls-Universität Heidelberg,
Center for Molecular Biology Heidelberg (ZMBH)
: “Analysis  of the cellular and humoral  immune response against the Merozoite-Surface-Protein-1 of the malaria parasite  Plasmodium falciparum”, Supervisor:  Prof. H. Bujard

01/1999 – 09/1999

Diploma German Cancer Center Heidelberg (DKFZ):
“Mutation Analysis of the ATM gene in Mantle Cell Lymphoma“, Department of „Molecular Genetics“, Supervisor: Prof. P. Lichter

06/1996 – 08/1999

Diploma studies in Biology at the Ruprecht-Karls-Universität, Heidelberg, Molecular Biology, Pharmacology und Zoology

10/1993 – 04/1996

Study of Biology at the University Stuttgart-Hohenheim, Bachelor in Physics, Chemistry, Botany und Zoology

19851993

Georg Büchner Gymnasium Winnenden, Chisipite High School, Harare, Zimbabwe

 

Publications (Auswahl)

 

  • Opel, D., A. Schnaiter, D. Dodier, M. Jovanovic, A. Gerhardinger, I. Idler, D. Mertens, L. Bullinger, S. Stilgenbauer and S. Fulda (2015). "Targeting inhibitor of apoptosis proteins by Smac mimetic elicits cell death in poor prognostic subgroups of chronic lymphocytic leukemia." Int J Cancer 137(12): 2959-2970. IF 5.007
  • Garding, A., N. Bhattacharya, R. Claus, M. Ruppel, C. Tschuch, K. Filarsky, I. Idler, M. Zucknick, M. Caudron-Herger, C. Oakes, V. Fleig, I. Keklikoglou, D. Allegra, L. Serra, S. Thakurela, V. Tiwari, D. Weichenhan, A. Benner, B. Radlwimmer, H. Zentgraf, S. Wiemann, K. Rippe, C. Plass, H. Dohner, P. Lichter, S. Stilgenbauer and D. Mertens (2013). "Epigenetic upregulation of lncRNAs at 13q14.3 in leukemia is linked to the In Cis downregulation of a gene cluster that targets NF-kB." PLoS Genet 9(4): e1003373. IF 8.694.
  • Garding, A., N. Bhattacharya, S. Haebe, F. Muller, D. Weichenhan, I. Idler, K. Ickstadt, S. Stilgenbauer and D. Mertens (2013). "TCL1A and ATM are co-expressed in chronic lymphocytic leukemia cells without deletion of 11q." Haematologica 98(2): 269-273. IF 5.
  • Bhattacharya, N., S. Diener, I. S. Idler, T. F. Barth, J. Rauen, A. Habermann, T. Zenz, P. Moller, H. Dohner, S. Stilgenbauer and D. Mertens (2011). "Non-malignant B cells and chronic lymphocytic leukemia cells induce a pro-survival phenotype in CD14+ cells from peripheral blood." Leukemia 25(4): 722-726. IF 9.561
  • Bhattacharya, N., S. Diener, I. S. Idler, J. Rauen, S. Habe, H. Busch, A. Habermann, T. Zenz, H. Dohner, S. Stilgenbauer and D. Mertens (2011). "Nurse-like cells show deregulated expression of genes involved in immunocompetence." Br J Haematol 154(3): 349-356. IF 4.942
  • Idler, I., N. Bhattacharya, H. Dohner, S. Stilgenbauer and D. Mertens (2011). "Immune modulatory agents in hematopoietic malignancies." Cancer Treat Rev 37 Suppl 1: S2-7. IF 6.811
  • Bhattacharya, N., A. Sarno, I. S. Idler, M. Fuhrer, T. Zenz, H. Dohner, S. Stilgenbauer and D. Mertens (2010). "High-throughput detection of nuclear factor-kappaB activity using a sensitive oligo-based chemiluminescent enzyme-linked immunosorbent assay." Int J Cancer 127(2): 404-411. IF 4.942
  • Giannopoulos, K., D. Mertens, A. Buhler, T. F. Barth, I. Idler, P. Moller, A. Krober, J. Greiner, S. Chocholska, A. Dmoszynska, J. Rolinski, H. Dohner, S. Stilgenbauer and M. Schmitt (2009). "The candidate immunotherapeutical target, the receptor for hyaluronic acid-mediated motility, is associated with proliferation and shows prognostic value in B-cell chronic lymphocytic leukemia." Leukemia 23(3): 519-527. IF 8.634
  • Idler, I., K. Giannopoulos, T. Zenz, N. Bhattacharya, M. Nothing, H. Dohner, S. Stilgenbauer and D. Mertens (2009). "Lenalidomide treatment of chronic lymphocytic leukaemia patients reduces regulatory T cells and induces Th17 T helper cells." Br J Haematol 148(6): 948-950. IF 4.942
  • Mertens, D., A. Philippen, M. Ruppel, D. Allegra, N. Bhattacharya, C. Tschuch, S. Wolf, I. Idler, T. Zenz and S. Stilgenbauer (2009). "Chronic lymphocytic leukemia and 13q14: miRs and more." Leuk Lymphoma 50(3): 502-505. IF 2.492
  • Schaffner, C., I. Idler, S. Stilgenbauer, H. Dohner and P. Lichter (2000). "Mantle cell lymphoma is characterized by inactivation of the ATM gene." Proc Natl Acad Sci U S A 97(6): 2773-2778. IF 9.643

 

 

Anmerkung: Die Gesamtkoordination der EURAT-Gruppe hatte bis August 2013 Frau Dr. Grit Schwarzkopf, von 2013-2014 Herr Dr. Christoph Schickhardt und von 2014-28.02.2017 Herr Sebastian Schuol inne. Die Stelle wurde von 02.2017- 05.2018 durch Herrn Dr. Christoph Schickhardt kommissarisch vertreten.

 

Verantwortlich: E-Mail
Letzte Änderung: 25.10.2018
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