Molecular anatomy of the developing neuromuscular junction

Witzemann Veit Witzemann

Department of Cellphysiology
MPI for Medical Research
Jahnstr. 29
69120 Heidelberg

Phone: +49-6221-486475
Fax:  +49-6221-486459
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Research Summary

The formation of the neuromuscular junction involves reciprocal interactions between the presynaptic nerve terminal and the postsynaptic muscle fiber. We generate genetically manipulated mouse models to modulate synaptic activity by changing the functional properties of the postsynaptic signaltransducers, the acetylcholine receptors (AChR) or by inactivating conditionally other synaptic regulators. These studies lead to the analysis of disorders that are caused by defective neuromuscular junctions.

Structure of the Group

Group Leader:  Veit Witzemann
Postdoctoral fellows:  Frédéric Chevessier, Pessah Yamapolsky
PhD-Students:  Pier-Giorgio Pacifici
Undergraduates:  Ulrike Mersdorf, Susi Zobeley


Editor: Email
Latest Revision: 2013-03-06
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