Molecular pathogenesis of genetic disorders

Gr-11-10-18 Gudrun Rappold

Department of Human Molecular Genetics
Institute of Human Genetics
University of Heidelberg
INF 366
69120 Heidelberg
Phone:  +49-6221-565059
Fax:  +49-6221-565155

Research Summary

Our team works on the molecular mechanism underlying human developmental disease. A special focus is on neurodevelopmental disorders and the genetic etiology of intellectual disability and autism, but also on the regulation of transcription factors in growth and development. Our work employs genome-editing, cell culture-based system as well as induced pluripotent stem cells and animal models. We aim at understanding how mutations correlate with disease, how genes are regulated and how they contribute to differentiation and development.

Structure of the Group

Group Leader:  Gudrun Rappold
Scientists/Postdoctoral fellows:  Simone Berkel, Laetitia Francelle, Henning Fröhlich, Sandra Hoffmann
PhD Students:  Flavia-Bianca Cristian, Ahmed Eltokhi, Kristin Raedecke, Simon Sumer, Jing Wang
MD students:  Marie-Luise Kollmeyer, Birgit Körtje, David Rheinert, Manuel Stuhlinger, Christine Unsicker
Undergraduates:  Viktoria Frajs, Jasmin Gogel
Technicians:  Ralph Roeth, Birgit Weiss


Editor: Email
Latest Revision: 2019-12-04
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