Annarita Patrizi Neuronal Signaling and Morphogenesis Laboratory German Cancer Research Center Im Neuenheimer Feld 581 69120 Heidelberg   Phone:  +49 6221 42-1551 Fax:  +49 6221 42-1559 eMail:  a.patrizi@dkfz-heidelberg.de Website:  https://www.dkfz.de/en/neuronale-signalwege-morphogenese/index.php

Research Summary

Neuronal development and maturation rely on extrinsic and intrinsic cues to optimally guide neuronal identity and maintenance. Extrinsic signals arise mainly from cerebrospinal fluids that are produced by the choroid plexus, a specialized epithelial layer located in each ventricle in the brain. Our group focuses on the unbiased identification of choroid plexus-secreted instructive signals that exert an endocrine-like effect on cortical cells, governing their maturation in normal and disease conditions.

Structure of the Group