Molecular mechanisms underlying chronic pain

Rohini Kuner Department of Pharmacology INF 366 69120 Heidelberg Germany   Phone:  +49-6221-548289 Fax:  +49-6221-548549 Email:  rohini.kuner@pharma.uni-heidelberg.de Website:  https://www.medizinische-fakultaet-hd.uni-heidelberg.de/einrichtungen/institute/pharmakologie/forschung/arbeitsgruppe-kuner

Research Summary:

We aim at understanding molecular mechanisms underlying chronic pain resulting from long-lasting inflammation or cancer. A major focus is laid on addressing signalling mechanisms which underlie activity-dependent changes in primary sensory neurons transmitting pain (nociceptors) and their synapses in the spinal dorsal horn. Our current work spans molecular, genetic, behavioural, electrophysiological and imaging approaches in vitro as well as in vivo in rodent models of pathological pain.

Structure of the Group