Development of Nerve Cells and Generation of Neuronal Diversity
To understand how population-specific and general neuronal properties are acquired during neuronal development, we analyze the expression of genes coding for neurotransmitter synthesizing enzymes and synaptic proteins. In sympathetic ganglia growth factors from the BMP family induce early wide-spread expression of both classes of genes. GDNF-family ligands are later involved in the differentiation of neuronal sub-types.
Structure of the Group:
Group Leader: Uwe Ernsberger