Functional analysis of cortical neuronal networks
Institute for Physiology and Pathophysiology
University of Heidelberg
Our group is interested in coordinated patterns of activity in neuronal networks. We focus on network oscillations in memory-related systems, especially the mammalian hippocampal formation. Using in vitro and in vivo electrophysiological methods, we analyze patterned activity at different system levels from single cells to freely-moving mice. Leading questions are:
- Which mechanisms underlie coherent network oscillations?
- How are cells bound into co-active ensembles?
- How do different (oscillatory) patterns overlap and interact?
- How stable or plastic are multi-neuronal network patterns?
Special interests are devoted to ectopic action potential generation in axons and to the function and plasticity of GABAergic synapses.
We cooperate with colleagues from computational neuroscience, molecular neurobiology and neuroanatomy including Hilmar Bading (Heidelberg), Heinz Beck (Bonn), Michael Frotscher (Hamburg), Martin Korte (Braunschweig), Ulrike Müller (Heidelberg), Adriano Tort (Natal, Brazil), Roger D. Traub (New York), and others.
Structure of the Group
|Group Leader:||Andreas Draguhn|
|Postdoctoral fellows:||Martin Both, Claus Bruehl, Alexei Egorov, Dimitri Hefter, Evgueni Ianovskii, Andrei Rozov, Christian Thome|
|PhD students:||Matthias Klumpp, Nadja Lehmann, Märt Rannap, Jiaojiao Zhang|
|MD students:||Paul Grube, Maximilian Hammer, Alexander Hodapp, Nikolas Stevens, Gary Wegen|
|Lab Management:||Katja Lankisch, Tina Sackmann, Nadine Zuber|