Molecular and cellular basis of normal and pathologic cognition, learning and memory and mental retardation

Research Summary:

We study normal and pathological learning and memoryin molecular terms. Although the role of genes in basicsynaptic functions can be studied in neurons in cell culturein vitro, the role of genes in cognition can be studied onlyin the functional brain. Therefore, we create targetedand regulated genetic modifications of candidate genesspecifically in the areas of the rodent brain involved inlearning and memory. The genetically modified mice andrats are then studied using current methods of molecularbiology, electrophysiology, behavior and pharmacology

Structure of the Group: