26.06.2018    13:00

Akademische Mittagspause


Das geniale Gedächtnis

Prof. Dr. Hannah Monyer


Plöck 70
69117 Heidelberg-Altstadt


27.06.2018    13:00

IZN Seminar


A genetically encoded system for cell-type-specific, high-resolution modification of neuronal network activity in vivo

Sidney Cambridge (AG Cambridge)


Sensations driving oxytocin neurone to social behaviour

Diego Benusiglio (AG Grinevich)


HS2, Im Neuenheimer Feld 306, Heidelberg


01 & 02.07.2018

IZN Retreat


The Gut-Brain Axis in Health and Disease


Kloster Schöntal


04.07.2018    13:00

Neurobiology / SFB1158 Lecture


Dosage matters: kainate receptor protein levels and mental disease


Prof. Juan Lerma
Instituto de Neurociencias CSIC-UMH
San Juan de Alicante, Spain


HS2, Im Neuenheimer Feld 306, Heidelberg


12.07.2018    13:00

Akademische Mittagspause


Lernen und Vergessen: Von Fliegen und Menschen

Prof. Dr. Christoph Schuster


Plöck 70
69117 Heidelberg-Altstadt


Welcome to the IZN Home Page
Selected cells
Kuner T Fig1
Pauen Fig1
Poggi Figure2
Rappold Fig1
Holstein Fig1

Researchers discover receptor for the protein fragment APPsα mediating its physiological function

A cleavage product of the Alzheimer's APP protein stimulates nerve cell communication and memory. The protein fragment, known as APPsα, has neuroprotective properties and acts as a signal molecule on other nerve cells. But how does it influence brain functions?

An international research team led by Prof. Dr Ulrike Müller Externer Inhalt of the IZN has gained new insights into the molecular mechanism underlying its physiological functions. Full article...Externer Inhalt

Photo: Max Richter, Müller research group
Neuroprotective role of APPsα: A histological section through the hippocampus is depicted in the background. The red staining shows APPsα in neuronal cell bodies. The green staining shows the dendritic processes of nerve cells.

EMBL scientists discover how a molecule’s role changes from simple metabolite to instructive signal

ArendtAmong developmental biologists, the signalling molecule retinoic acid is well known for its role in building the vertebrate body. Not much is known, however, about how such signals emerge in evolution. To investigate this, the IZN's Arendt Externer Inhalt lab at EMBL in Heidelberg has studied the role of retinoic acid signalling in a marine worm. In the study published in Science Advances Externer Inhalt, the team and its collaborators show that in the worm, retinoic acid acts like a metabolic timer that helps neurons to form at the right time and place during development.

Image: Mette Handberg-Thorsager/EMBL



Open positions at the IZN

  • The research group of Prof. Andreas Draguhn is offering a PhD position to help untangle the molecular mechanisims by which Bcl11b/Ctip2 regulates development, maintenance and network-level functions of mossy fiber connectivitiy in CA3. The project combines state-of-the-art molecular, ultrastructural as well as electrophysiological strategies, and it will qualify PhD students both in the field of molecular/cellular neurobiology as well as cellular/systems neurophysiology. Adobe posted 06.2018
  • The research group of Dr. Kevin Allen is seeking a highly motivated PhD student to work on the neuronal basis of spatial behavior. The student will use a wide array of techniques to study system neuroscience, including in vivo tetrode recordings in mice, optogenetics, behavioral testing, analysis of large databases and histological analysis. Adobe posted 05.2018
  • A PhD position is open at the Department of Neurophysiology lead by Prof. Treede to validate electrophysiological techniques on human models of pain. The main objective of the work is to improve the translatability of recordings in pain pathways of healthy subjects and preclinical species. The successful candidate will investigate the analgesic effects in the brain, the spinal cord and the peripheral nervous system. Adobe posted 05.2018
  • The research group of Dr. Sidney Cambridge (Department of Functional Neuroanatomy, Prof.Dr. Thomas Kuner) is looking for a highly motivated and well-trained student (f/m) for a Masters research project in cellular neurophysiology. The project will involve genetic manipulation of neuronal activity in a small population and assessing network changes in activity as compensatory homeostatic mechanisms. Adobe posted 05.2018
  • A PhD position in Neurobiology and Alzheimer Research is available in the laboratory of Prof. Ulrike Müller Externer Inhalt studying the synaptic roles of the APP gene family and their processing products. Techniques employed include state-of-the-art molecular biology, biochemistry, imaging and work with genetically modified mouse mutants (gain and loss of function studies) and viral vectors. Adobe posted 04.2018
  • The Ruiz de Almodóvar group is interested in the mechanisms of neurovascular development in mice and is looking for a motivated HiWi student to help with basic experimental techniques such as mouse genotyping, cell culture and histology. Adobe posted 03.2018
  • The Developmental Neurobiology group of Prof. Elisabeth Pollerberg is looking for a highly motivated postdoc whose project will focus on the interactions of cell adhesion molecules with other types of proteins and the impact of these interactions on axon elongation and navigation. Substantial amounts of data have already been collected for several projects and the postdoc is expected to complete and publish these studies. In addition, a new translational project could be started aiming at the improvement of axon regeneration. Adobe posted 02.2018



Managing Director:
Prof. Dr. Hilmar Bading
IZN-Neurobiology, University of Heidelberg
Im Neuenheimer Feld 364
D-69120 Heidelberg, Germany

Phone:  +49 - 6221 - 54 8218
Fax:  +49 - 6221 - 54 6700
email:  Bading@nbio.uni-heidelberg.de


Dr. Otto Bräunling
IZN-Neurobiology, University of Heidelberg
Im Neuenheimer Feld 364, 1.OG
D-69120 Heidelberg, Germany

Phone:  +49 - 6221 - 54 8694, 56 39007
Fax:  +49 - 6221 - 54 6700
email:  Braeunling@nbio.uni-heidelberg.de


Administration & Information:
Irmela Meng
IZN-Neurobiology, University of Heidelberg
Im Neuenheimer Feld 364, 1.OG
D-69120 Heidelberg, Germany

Phone:  +49 - 6221 - 54 8219
Fax:  +49 - 6221 - 54 6700
email:  Sekretariat@nbio.uni-heidelberg.de

Webmaster contact: WebmasterIZN@uni-heidelberg.de
Latest Revision: 2018-06-20
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