Development of immune modulatory RNAs

Cartoon of how immune modulatory RNAs are working — © Georg Stoecklin, MI3, UMM

The expression of numerous cytokines is controlled by different RNA-binding proteins (RNA-BPs), which regulate the stability and translation of cytokine mRNAs. In “Synthetic Immunology” project 4, we design and optimize immune-modulatory RNAs (imodRNAs) with the aim to sequester specific RNA-BPs. Upon packaging and delivery, imodRNAs are expected to alter cytokine expression and thereby modulate immune responses.

Staff

Table

Name	Function

Name	Function
Georg Stoecklin	Principal Investigator
Kerstin Göpfrich	Principal Investigator
Andres Jeschke	Principal Investigator
Janina Lehmann	Postdoc
Hsu-Min Sung	Postdoc
Chih-Yuan Kao	PhD student
Joachim Spatz	Principal Investigator
Nina Papavasiliou	Principal Investigator
Michael Platten	Principal Investigator
Adelheid Cerwenka	Principal Investigator