Peer-reviewed publications

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(since 2000)

Ring. S, Weyer, S., Kilian, S. B., Waldron, E., Pietrzik, C. U., Filippov, M., Herms, J., Buchholz, C., Eckman, C. B., Martin Korte, M., Wolfer, D. P. and Müller, U. (2007).The secreted APPsα domain is sufficient to rescue the anatomical, behavioral, and electrophysiological abnormalities of APP deficient mice. J. Neuroscience 27, 7817-7826.

Back S, Haas P, Tschape JA, Gruebl T, Kirsch J, Müller, U., Beyreuther K, and Kins S.(2007). Beta-amyloid precursor protein can be transported independent of any sorting signal to the axonal and dendritic compartment. J Neurosci Res., (Epub ahead of print: DOI: 10.1002/jnr.21239)

Hirzel*, K., Müller*, U. , Latal*, A. T., Hülsmann, S., Grudzinska, J., Seeliger, M. W.,Heinrich Betz, H. and Laube, B. (2006). Hyperekplexia phenotype of glycine receptor α1 subunit mutant mice identifies Zn2+ as an essential endogenous modulator of glycinergic neurotransmission. * authors contributed equally. Neuron 52, 679.

Anliker, B. and Müller, U. (2006). The functions of the mammalian amyloid pr cursor protein and related amyloid precursor-like proteins. Neurodegenerative Diseases 3, 239-246.

Hösl, K., Reinold, H., Müller, U., Narumiya, S., Zeilhofer, H. U. (2006). Spinal prostaglandin E receptors of the EP2 subtype and the glycine receptor α3 subunit, which mediate central inflammatory hyperalgesia, do not contribute to pain after peripheral nerve injury or formalin injection. Pain 126, 46-53.

Hebert, S.S., Serneels, L. , Tolia, A., Craessaerts, K., Derks,C., Filippov, M. A., Müller, U., DeStrooper, B. (2006). Regulated intramembrane proteolysis of amyloid precursor protein and regulation of expression of putative target genes. EMBO reports 7, 739-45.

Siemes, C., Quast, T., Kummer, C., Wehner, S., Kirfel, G., Müller, U. and Herzog, V.(2006). Keratinocytes from APP/APLP2 deficient mice are impaired in proliferation, adhesion and migration in vitro. Exp Cell Res. 312, 1939-49.

Ivanova, E., Müller, U. and Wässle, H. (2006) Characterization of the glycinergic
input to bipolar cells of the mouse retina. Eur. J. of Neuroscience 23, 350-364.

Endres, K. Postina, R., Schröder, A., Müller, U. and Fahrenholz, F. (2005). Shedding of the amyloid precursor protein-like protein APLP2 by disintegrin-metalloproteinases. FEBS J. 272, 5808-5820.

Grimm, M. O. W., Grimm, H. S., Pätzold, A. J., Zinser, E. G., Halonen, R., Duering,
M., Tschäpe, J.-A., De Strooper, B., Müller, U., Shen, J. and Hartmann, T. (2005). Regulation of cholesterol and sphingomyelin metabolism by amyloid-β and presenilin. Nat. Cell. Biol. 7, 1118-1123.

Soba, P. , Eggert, S., Zentgraf, H., Siehl, K., Kreger, S., Löwer,A., Langer, A.,
Merdes, G., Paro, R.,. Masters, C. L., Müller,U., Kins, S. and Konrad Beyreuther. (2005). Homo- and hetero-dimerization of APP family members promotes intercellular adhesion. EMBO J. 24, 3624-3634.

Pardossi-Piquard, R. Petit, A., Kawarai, T., Sunyach, C. Alvers da Costa, C.
Vincent, B., St. Ring, S. , DÁdamio, L., Shen, J., Müller, U., George Hyslop, P. and Checler, F. (2005). Presenilin-dependent transcriptional control of the Aβ degrading enzyme neprilysin by intracellular domains of APP and APLP. Neuron 46, 541-554.

Reinold, H., Ahmadi, S.,. Depner. U. B., Layh, B., Heindl, C., Hamza, M., Pahl, A., Brune, K., Narumiya, S., Müller, U. and Zeilhofer H. U. (2005). Central Inflammatory Hyperalgesia Is Mediated by Spinal Prostaglandin E Receptors of the EP2 Subtype. The Journal of Clinical Investigation 115, 673-679.

Lopez- Sanchez, M., Müller, U. and Frade, J. M. (2005). Lengthening of G2/mitosis in cortical precursors from mice lacking β-amyloid precursor protein. Neuroscience 130, 51-60.

Herms, J., Anliker, B., Heber, S., Ring. S., Fuhrmann, M., Kretzschmar, H., Sisodia, S. and Müller, U. (2004). Cortical Dysplasia Resembling Human Type 2 Lissencephaly in Mice Lacking all Three APP-Family Members. The EMBO J. 23, 4106 – 4115.

Haverkamp, S., Müller, U., Zeilhofer, H. U., Harvey, R. J. and Wässle, H. (2004). Diversity of Glycine Receptors in the Mouse Retina: Localization of the α2 Subunit . J. of Comparative Neurology 477, 399-411.

Harvey, R., Depner, U.,Wässle,H., Ahmadi, S., Heindl, C., Reinold, H., Smart, T., Harvey, K., Schütz, B., Akbari, O., Zimmer, A., Poisbeau, P., Welzl, H.,Wolfer, D. P., Betz, H., Zeilhofer, U., and Müller, U. (2004). GlyRα3: an essential target for spinal PGE2-mediated inflammatory pain sensitization. Science 304, 884.

Caille, I., Alliquant, B., Dupont, E., Bouillot, C., Langer, A., Müller, U. and Pronchiantz, A. (2004). Soluble form of Amyloid precursor protein regulates proliferation of Progenitors in the adult subventricular zone. Development 131, 2173.

Haverkamp, S., Müller, U., Harvey, K., Harvey, R.J., Betz, H. and Wässle, H. (2003). Diversity of Glycine receptors in the mouse retina: Localization of the α3 subunit. J. of Comparative Neurology 465, 524-539.

Herreman, A., Van Gassen, G., Dillen, K., Bentahir, M., Nyabi, M., Craessaerts, K., Müller, U., Annaert, W., and De Strooper, B. (2003). Gamma-secretase activity requires the presenilin dependent trafficking of nicastrin through the Golgi apparatus but not its complex glycosylation. J. Cell Science 116, 1128-1136.

Tremml, P., Lipp, H.-P., Müller, U. and Wolfer, D. P. (2002). Enriched early experiences of mice underexpressing the β-amyloid precursor protein restore spatial learning capabilities but not normal openfield behavior of adult animals. Genes, Brain and Behavior 1, 230-241.

Mbebi, C., See, V., Mercken, L., Pradier, L., Müller, U. and Loeffler, J.-P. (2002). Amyloid precursor protein familly-induced neuronal death is mediated by impairment of the neuroprotective calcium/calmodulin protein kinase IV-dependent signaling pathway J. Biol. Chem. 277, 20979-20990.

Leissring, M. A., Murphy,M. P., Mead, T. R., Akbari, Y., Sugarman, M.C., Jannatipour, M., Anliker, B., Müller, U., Saftig, P., De Strooper, B., Wolfe, M. S., Golde , T. E. and LaFerla, F. M. (2002). A physiologic signaling role for the γ-secretase-derived intracellular fragment of APP. Proc. Natl. Acad. Sci. USA 99, 4697.

Behr, M., Schieferdecker, K., Buhr, P., Buter, M., Petsophonsakul, W., Sirirungsi, W., Redmann-Müller, I., Müller, U., Prempracha, N. and Jungwirth, C. (2001). Interferon-stimulated response element (ISRE)-binding protein complex DRAF1 is activated in Sindbis virus (HR)-infected cells. J. Interferon Cytokine Res. 21, 981.

Heber, S., Herms, J., Gajic, V., Hainfellner, J., Aguzzi, A., Rülicke, T., Kretzschmar, H., von Koch, C., Sisodia, S., Tremml, P., Lipp, H.-P., Wolfer, D. P. and Müller, U. (2000). Mice with combined gene knockouts reveal essential and partially redundant functions of Amyloid precursor protein family members. J. Neurosci. 20, 7951-7963.


Müller, U. and Kins, S. (2002). APP on the move (Review). Trends in Molecular Medicine 8,152.

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Latest Revision: 2013-02-12
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