Publications
Peer-reviewed publications
Search for Kins, S. Publications on 
Back, S., Haas, P., Tschäpe, J.-A., Gruebl, T., Kirsch, J., Müller, U., Beyreuther, K., Kins, S. (2007). In neurons APP can be transported independent of any sorting signal to the axonal and dendritic compartment. J Neurosci Res 25, 1079-1086.
Rusu, P., Jansen, A., Soba, P., Kirsch, J., Löwer, A., Merdes, G., Kuan, Y.-H., Jung, A., Beyreuther, K., Kjaerulff, O., Kins, S. (2007) Axonopathy in APP transgenic Drosophila depends on the NPTY motif and is paralleled by defects in synaptic plasticity. Eur J Neurosci 25, 1079-86.
Kuan, Y.-H., Grübl, T., Soba, P., Eggert, S., Nesic, I., Kirsch, J., Beyreuther, K., Kins, S. (2006) The processing and anterograde transport of APP, APLP1 and APLP2 is affected by the carboxyl-terminal binding partner PAT1a. J Biol Chem 281, 40114-123.
Kins, S., Lauther, N., Szodorai, A., and Beyreuther, K. (2006) Subcellular trafficking of the APP gene family and its pathogenic role in Alzheimer’s Disease. Neurodegener Dis 3, 218-26.
Horster F, Schwab MA, Sauer SW, Pietz J, Hoffmann GF, Okun JG, Kolker S, Kins S. (2006) Phenylalanine reduces synaptic density in mixed cortical cultures from mice. Pediatr Res 59, 544-8.
Soba, P., Eggert, S., Zentgraf, H., Kreger, S., Löwer, A., Merdes, G., Paro, R., Masters, C.L. Müller, U., Kins, S.*, Beyreuther, K.* (2005) Cell interactions are promoted by trans-dimerization of APP family members, arranged as homo- or hetero-complexes in synaptic membranes. EMBO J 24, 3624-36
von Rotz, R.C.*, Kins, S.*, Hipfel, R., von der Kammer, H., Nitsch, R.M. (2005) The cytosolic ring finger protein dactylidin is selectively upregulated in brains of patients with Alzheimer’s disease. Eur J Neurosci 21, 1289-98.
Lazarov, O., Morfini, G.A., Szodorai, A., Kins, S., Lee, V., Trojanowski, J., Price, D., Brady, S.T., Sisodia, S.S. (2005) Axonal Transport, APP, Kinesin and the Processing Apparatus: Revisited. J Neurosci 25, 2386-95.
Kins, S., Kurosinski, P., Nitsch, R.M. and Götz, J. (2003) Hyperphosphorylation and somatodendritic localization of tau in PP2A dominant negative mutant mice is associated with activation of ERK and JNK signaling. J Am Path 163, 833-843.
Schmidt, K.*, Kins, S.*, Schild, A., Nitsch, R.M., Hemmings,B and Gotz, J. (2003) Diversity, developmental regulation and distribution of murine PR55/B subunits of protein phosphatase 2A. Eur J Neurosci 16, 2039-48.
Fuhrmann, J.C., Kins, S., Kirsch, J., Kneussel, M., Betz, H. (2002) Gephyrin interacts with DLC-1/PIN and DLC-2, components of the cytoplasmic dynein complex. J Neurosci 22, 5393-402.
Steinhoff, T., Moritz, E., Wollmer, M.A., Mohajeri, M.H., Kins, S. and Nitsch, R.M. (2001) Increased cystatin C in astrocytes of transgenic mice expressing the K670N-M671L mutation of the amyloid precursor protein and deposition in brain amyloid plaques. Neurobiol Dis 8, 647-54.
Kins, S., Crameri, A., Evans, D. R., Hemmings, B. A., Nitsch, R. M., and Gotz, J. (2001) Reduced PP2A activity induces hyperphosphorylation and altered compartmentalization of tau in transgenic mice. J Biol Chem 276, 38193-200.
Grosskreutz, Y., Hermann, A., Kins, S., Fuhrmann, J. C., Betz, H., and Kneussel, M. (2000) Identification of a gephyrin-binding motif in the GDP/GTP exchange factor collybistin. Biol Chem 382, 1455-62.
Ramming, M.*, Kins, S.*, Werner, N., Hermann, A., Betz, H., and Kirsch, J. (2000) Diversity and phylogeny of gephyrin: tissue-specific splice variants, gene structure, and sequence similarities to molybdenum cofactor-synthesizing and cytoskeleton-associated proteins. Proc Natl Acad Sci USA 97, 10266-71.
Kins, S., Betz, H., and Kirsch, J. (2000) Collybistin, a newly identified brain-specific GEF, induces submembrane clustering of gephyrin. Nat Neurosci 3, 22-9.
*equal contribution
Book Chapters
Kins, S. and Beyreuther, K. (2007) Alzheimer’s Disease. In: „Encyclopedia of Molecular Mechanisms of Disease“, Springer Verlag, in press.
Chen F, Ferrari A, Schild A, Kurosinski P, David D, Hoerndli F, Pennanen L, Kins S, van Dorpe J, Nitsch RM, Götz J (2003) Amyloid-induced neurofibrillary tangle formation. In Alzheimer’s disease and related disorders: Research advances, K. Iqbal, B. Winblad, ed (Ana Aslan International Foundation). Reviews
Kins, S. and Beyreuther, K. (2006) Teasing out the tangles. Nat Med 12, 764-5.
Götz, J., Ittner, L.M., and Kins, S. (2006) Do axonal defects in tau and APP transgenic animals model axonopathy in Alzheimer’s disease? J Neurochem 98, 993-1006.
Müller, U. und Kins, S. (2001) APP on the move. Trends Mol Med 8, 152-5.
