Nuclear Calcium Signalling in the Dialogue between Synapse and Nucleus: Role in Neuronal Survival and Memory

badingHilmar Bading

Department of Neurobiology
IZN
University of Heidelberg
INF 364,
69120 Heidelberg
Germany

 

 

Phone:  +49-6221-548218
Fax:  +49-6221-546700
eMail:  Hilmar.Bading@uni-hd.de
Website:  www.izn.uni-hd.de/researchgroups/bading

 

Research Summary

Synaptic activity-induced changes in the concentration of intracellular calcium control many processes in neurons including gene expression. Calcium signals propagating towards the cell soma and the nucleus are key mediators of synapse-to-nucleus communication. Nuclear calcium controls CREB/CBP-dependent transcription and regulates genomic programs critical for neuronal survival, plasticity and memory.

Structure of the Group

Group Leader:  Hilmar Bading
   
Postdoctoral fellows:  Carlos Bas Orth, C. Peter Bengtson, Otto Bräunling, Bettina Buchthal, Eckehard Freitag, Anna Hertle, David Lau, Daniela Mauceri, Sara Monaco, Ana Oliveira, Priit Pruunsild, Yan-Wei Tan, Yan Yu
PhD students:  Stefanie Hayer, Thekla Hemstedt, Thomas Lissek
Students:  Ann-Kathrin Kerz, Stephanie Rothe
Technicians:  Iris Bünzli‑Ehret, Andrea Hellwig, Ursula Weiss

 

Editor: A. Summerfield
Latest Revision: 2016-02-18
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