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Biotechnology
PUBLICATIONS:
Pharmacology, Pytomedicine
Plant
Secondary metabolism, cell cultures, biotechnology
Bioactive natural products (alkaloids, terpenoids, saponins,
isoflavones, glycosides)
PUBLICATIONS:
Phytochemistry:
Terpenoids, Phenolics, Alkaloids (exept PAs and QAs)
Pyrrolizidine
alkaloids
Lupins
and quinolizidine alkaloids
- Isolation
and characterisation
- Capillary
GLC, HPLC
- GLC-MS,
FAB-MS; LC-MS, NMR
- Quality
control for quinolizidine (lupin),pyrrolizidine and solanum alkaloids and other
natural products and toxins
Pharmacology & toxicology of natural products or phytopharmaceutical
drugs
PUBLICATIONS:
Pharmacology,
Pytomedicine
-
Determination of the mode of action (elucidation of molecular targets), e.g. binding
to neuroreceptors, interaction with ion channels and other elements of signal
transduction, DNA, RNA, protein biosynthesis, biomembranes, haemolysis, enzyme
inhibition, Antioxidants, GSK
- Modulation
of telomerase in tumour cells
- Modulation
of ABC transporters by natural products
-
Induction of apoptosis or necrosis by natural products in tumour cells and trypanosomes
- HET-CAM
assay for anti-inflammatory activities, angiogenesis, irritation
-
Antidiabetic and estrogenic properties of natural products
-
Uptake
of biogenic compounds into cells (CaCo2, etc); study of diffusion and transport
mechanisms
Chemical Ecology
PUBLICATIONS:
Chemical
Ecology
- Role
& evolution of secondary metabolites in plants and herbivores
- Induction
of secondary metabolite formation by wounding or herbivory
- Evolution
of tolerance or insensitivity towards acquired defence chemicals in herbivores
- Coevolution
between plants and insects
- Geophagy
as a strategy to detoxify diets rich in secondary metabolites
- Degradation
of dietary secondary metabolites by ruminants and slugs
Molecular evolution / molecular ecology
PUBLICATIONS:
Evolution
general
Phylogeny
birds; molecular ecology
Phylogeny Reptiles
Phylogeny
Fishes
Phylogeny Insects
Phylogeny
Oligochaeta
Phylogeny Plants
- Evolution
of breeding systems and paternity analysis (reed warblers, falcons, shearwater,
owls,king
fisher etc); analysis by DNA
fingerprinting and microsatellite PCR
PUBLICATIONS:
Phylogeny
birds; molecular ecology
- Population
genetics and island biogeography (Aegean sea; Macaronesia; Tonga Islands; Sokotra,
Madagascar)
PUBLICATIONS:
Phylogeny
birds; molecular ecology
Ornithology,
Atlas work, Monitoring (see Phylogeny birds)
Falco
eleonorae
Calonectris diomedea
- Molecular
phylogeny & phylogeography of diurnal raptors (Accipitridae, Pandionidae, Cathartidae,
Falconidae), owls, anseriformes, flamingos, hornbills, parrots, bustards, gulls,
warblers, turdids, tits etc. (analysis of nucleotide sequences of mtDNA, ncDNA,
genomic fingerprinting with ISSR-PCR)
PUBLICATIONS:
Phylogeny
birds; molecular ecology
Phylogeny
Reptiles
- Molecular
phylogeny & phylogeography of reptiles (snakes, lizzards, agamids, turtles), fish
(Mormyridae)
PUBLICATIONS:
Phylogeny
Fishes
and
insects (Curculionidae, Arctiidae, Sphingidae)
PUBLICATIONS:
Phylogeny
Insects
- Molecular
phylogeny & phylogeography of plants (Fabaceae,
Solanaceae, Labiatae, Asphodelaceae, Cycadaceae) (analysis of rbcL, matk, atpb,
ITS I&II, ISSR-PCR)
PUBLICATIONS:
Phylogeny
Plants
Ion
channels and transporters
PUBLICATIONS:
Pharmacology,
Pytomedicine
- Isolation,
characterisation, cloning and expression of membrane transporters
- Proteomics
of membrane proteins
- Role
of ABC transporters for uptake or export of drugs
- Uptake
mechanism of secondary metabolites across intestinal epithelia
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